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Cagrilintide is an analogue of amylamine, a hormone produced by the pancreas in conjunction with insulin. Amylamine helps regulate satiety and slows digestion. Regular amylamine is rapidly broken down, so cagrilintide has been made more stable to provide a longer-lasting effect. The drug affects the brain, reduces appetite, and improves digestion.
Studies have shown that cagrilintide is effective and safe. A US study involved patients with type 2 diabetes taking semaglutide, cagrilintide, or both drugs together. All participants continued taking metformin.
| Parameter | cagrilintide (1.2 mg) + semaglutide (1.2 mg) | semaglutide (2.4 mg) | cagrilintide (2.4 mg) |
| Average reduction in glycated hemoglobin (HbA1c) | 2.2% | 1.8% | 0.9% |
| Average weight loss | 15.6% | 5.1% | 8.1% |
| Mean reduction in fasting plasma glucose | 3.3 mmol/L | 2.5 mmol/L | 1.7 mmol/L |
Clinical trials have shown that cagrilintide is effective in weight management and blood sugar reduction. It works on its own, and when combined with other medications, the effect is even greater.
Who is eligible for cagrilintide 20 mg in a syringe pen?
The most common side effects include decreased appetite, nausea, constipation, diarrhea, slow digestion, and a feeling of heaviness in the abdomen. These are usually related to the way the medication works and appear as the dose is increased. They are usually mild to moderate in severity and resolve on their own.
The drug Cagrilintide (Amylin) is not prescribed to patients:
Before starting treatment, be sure to consult your doctor to choose the right treatment regimen and ensure that you have no contraindications.
To reduce the risk of side effects, start taking cagrilintide at low doses and gradually increase them.
Missed a dose?
Get it as soon as possible, but no later than 5 days (120 hours). If more time has passed, simply skip the missed dose and take your next scheduled dose.
*For laboratory purposes and personal observations only.
The information is collected from numerous studies and analyses conducted over the years and is not intended to diagnose, treat, or prevent any diseases.
| Dose | 10mg, 20mg |
|---|



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